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Interaction between excess folate and low vitamin B12 status

Melanocytic proliferation means the dark line happens because there's a higher number of melanin cells in your nail

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Regarding skin lesions, bullous pemphigoid, a rare autoimmune skin disease, was found to be associated with the use of DPP-4 inhibitors in a retrospective analysis of more than 9,000 patients treated in Japan during the years 20092017